Early Modern era · 1545 – 1631
Cocoliztli epidemics
The Cocoliztli Epidemic or the Great Pestilence was an outbreak of a mysterious illness characterized by high fevers and bleeding which caused 5–15 million deaths in the North American territory of New Spain during the 16th century. The Aztec people called it cocoliztli, Nahuatl for pestilence.

- When
- 1545 – 1631
- Where
- Central America
- Era
- Early Modern
Before and after
Text from the Wikipedia article Cocoliztli epidemics, CC BY-SA 4.0